
Edetic acid
CAS No. 60-00-4
Edetic acid( Ethylenediaminetetraacetic acid,EDTA )
Catalog No. M22406 CAS No. 60-00-4
Edetic acid is a chelating agent commonly used in protein purification, both to eliminate contaminating divalent cations and to inhibit protease activity.
Purity : >98% (HPLC)






Size | Price / USD | Stock | Quantity |
500MG | 51 | In Stock |
![]() ![]() |
1G | 70 | In Stock |
![]() ![]() |
Biological Information
-
Product NameEdetic acid
-
NoteResearch use only, not for human use.
-
Brief DescriptionEdetic acid is a chelating agent commonly used in protein purification, both to eliminate contaminating divalent cations and to inhibit protease activity.
-
DescriptionEdetic acid is a chelating agent commonly used in protein purification, both to eliminate contaminating divalent cations and to inhibit protease activity.
-
In Vitro——
-
In VivoAnimal Model: Male Wistar rat model of cirrhosis induced by CCl4Dosage:60 mg/kg, 120 mg/kg, 240 mg/kg Administration: Intraperitoneal injection (i.p.); Three times per week for 3 weeks (during this period, CCl4 administration continued). After CCl4 and mineral oil mixture treatment (200 μL/mouse; i.p.; Three times per week for eight weeks).Result:Kept kept all the rats alive at the 60 mg/kg dose, but died at 120 and 240 mg/kg.Reduced fibrosis of the liver in surviving rats (20%).Animal Model:Male Wistar rat model of cirrhosis induced by CCl Dosage:60 mg/kg Administration:Intraperitoneal injection (i.p.); Three times per week for 11 weeks. EDTA and CCl4 were administered during 11 weeks, three times per week on alternate days). Intraperitoneal injection (i.p.); Three times per week. After CCl4 treatment (i.p.; Three times per week for eight weeks) (Therapeutic EDTA group: EDTA and CCl4 were administered for 3 weeks, three times per week on alternate days).Result:Increased sod activity by 50% in the preventive EDTA group. (Compared with untreated EDTA group)Increased Cp activity in the preventive EDTA (30%) and therapeutic EDTA (20%) groups. (Compared with the fibrotic group).Decreased mRNA expression of the pro-inflammatory molecule (TNF-α and LI-6) and the profibrogenic molecules (TGF-β and αCOLI) in both the prevention and treatment groups.
-
SynonymsEthylenediaminetetraacetic acid,EDTA
-
PathwayOthers
-
TargetOther Targets
-
RecptorOthers
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number60-00-4
-
Formula Weight292.24
-
Molecular FormulaC10H16N2O8
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?0.1 M NaOH : 6.67 mg/mL (22.8)
-
SMILESOC(=O)CN(CCN(CC(O)=O)CC(O)=O)CC(O)=O
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.D, Lebeau, P.E, et al. Direct analysis of ethylenediaminetetraacetic acid (EDTA) on concrete by reactive-desorption electrospray ionization mass spectrometry[J]. Talanta, 2015.
molnova catalog



related products
-
2-O-Galloylquercitri...
2''-O-Galloylquercitrin is a natural product from Acer ginnala.
-
Xanthinol Nicotinate
Xanthinol Nicotinate is a potent vasodilator that can easily enter the cell and causes an increase in glucose metabolism resulting in an increased energy.
-
Kanshone A
Kanshone A shows cytotoxic activity against P-388 cells.